WHAT CAUSES ACNE

• Sebaceous glands are attached to each hair follicle.

• Produces sebum (oily substance), which lubricates and protects the hair and skin.

• During puberty, hormones called androgens increase the size of the skin’s sebaceous glands.

• These glands can make too much sebum, which can clog pores.

• Pores become plugged with sebum(oil), dead skin cells, and bacteria (C. Acnes), causing skin eruptions.

• These blockages produce blackheads, whiteheads, nodules, and other pimples.

ACNE MECHANISM OF ACTION

• The purpose of the treatment is to selectively treat the sebaceous glands without causing thermal damage to the surrounding tissue.

• 1726 nm preferentially downregulates the sebaceous gland while other anatomies remain intact/ protected. The sebublasts (outer wall) are covered while the sebocytes are damaged.

TYPES OF ACNE

• Patients who do not have Mild to Severe inflammatory acne should not be treated.

• AviClear is not meant to treat comedonal acne.

Comedonal Acne

• Blackheads (Open Comedones): Open comedones on the skin that fill with excess oil and dead skin.

• Whiteheads (Closed Comedones): Closed comedones that remain closed by oil and dead skin.

Inflammatory Acne Papules

• Red, raised blemish on the skin’s surface with no whitehead.

Pustule

• Red, inflamed blemish with a white head.

Nodules

• Large, inflamed blemishes that are hard to touch and deeper in the skin.

• Typically, more painful.

Cystic:

• Huge, inflamed blemishes that are soft and fluid-filled under the skin’s surface.

• Can be very painful